Comparison of clinical and laboratory characteristics between adult-onset type 1 diabetes and latent autoimmune diabetes in adults.
نویسندگان
چکیده
A lthough they do not initially require insulin, diabetic adults presenting autoantibodies against -cells (antiGAD antibody [GADA] and anti–islet cell antibody [ICA]) more rapidly develop the need for insulinization, a fact characterizing latent autoimmune diabetes in adults (LADA) (1,2). Differences between LADA and type 2 diabetes (3–6) and between children and adults with type 1 diabetes (7) have been reported. In contrast, few studies are available comparing type 1 diabetes diagnosed during adulthood with LADA, with the results not being consistent (4,5,8). Therefore, the aim of the present study was to investigate clinical and laboratory parameters in patients with LADA compared with patients with adult-onset type 1 diabetes.
منابع مشابه
Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA) in Torbat-e Heydarieh, Iran
Background and Aims: The prevalence of latent autoimmune diabetes in adults (LADA) among diabetic patients is less recognized and underdiagnosed. The aim of this study was to determine the prevalence of LADA in type 2 diabetic patients and to compare the characteristics of these two groups in Torbat-e Heydarieh, Iran. Materials and Methods: Totally, 198 male and 277 female patients diagnosed ...
متن کاملSimilar genetic features and different islet cell autoantibody pattern of latent autoimmune diabetes in adults (LADA) compared with adult-onset type 1 diabetes with rapid progression.
OBJECTIVE To compare the clinical parameters, C-peptide levels, pattern of islet cell-specific autoantibodies, and prevalence of predisposing genotypes in subjects with latent autoimmune diabetes in adults (LADA) and those with adult-onset type 1 diabetes with rapid progression. RESEARCH DESIGN AND METHODS We evaluated the clinical parameters, C-peptide levels, and islet cell-specific autoant...
متن کاملCharacteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA)
Diabetes, one of the most commonly seen metabolic disorders, is affecting a major area of population in many developing as well as most of the developed countries and is becoming an alarming concern for the rising cost of the healthcare system. Latent Autoimmune Diabetes in Adults (LADA) is a form of diabetes which is less recognized and underdiagnosed type of diabetes which appears to have cha...
متن کاملImmunoregulatory differences between adult onset type 1 diabetes and latent autoimmune diabetes in adults
متن کامل
Latent Autoimmune Diabetes in Adults (LADA): The Prevalent Form of Adult-Onset Autoimmune Diabetes in a Region of India
Aims: We undertook a study to investigate the prevalence and general characteristics of patients with Latent autoimmune diabetes in adults (LADA). Methods: This was a cross-sectional investigation conducted in the National Capital Region of India. Total of 139 subjects were recruited in the study. All subjects were screened for Glutamic acid decarboxylase autoantibody (GADA). GADA was analysed ...
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عنوان ژورنال:
- Diabetes care
دوره 28 7 شماره
صفحات -
تاریخ انتشار 2005